Remdesivir in COVID-19: A critical review of pharmacology, pre-clinical and clinical studies
AK Singh, A Singh, R Singh, A Misra - Diabetes & Metabolic Syndrome …, 2020 - Elsevier
Background & aims Remdesivir is a broad spectrum anti-viral drug that has shown to inhibit
SARS-CoV-2, in vitro and in vivo. In absence of any effective treatment for SARS-CoV-2
infection (COVID-19), remdesivir has been tried for a compassionate use in severe COVID-
19. Newer randomized controlled studies that have recently become available, showed a
mixed result. We aimed to systematically search the literature to understand the
pharmacology and clinical effects of remdesivir in patients with COVID-19. Methods We …
SARS-CoV-2, in vitro and in vivo. In absence of any effective treatment for SARS-CoV-2
infection (COVID-19), remdesivir has been tried for a compassionate use in severe COVID-
19. Newer randomized controlled studies that have recently become available, showed a
mixed result. We aimed to systematically search the literature to understand the
pharmacology and clinical effects of remdesivir in patients with COVID-19. Methods We …
