[HTML][HTML] NAD+-precursor supplementation with L-tryptophan, nicotinic acid, and nicotinamide does not affect mitochondrial function or skeletal muscle function in …
NJ Connell, L Grevendonk, CE Fealy… - The Journal of …, 2021 - Elsevier
Background Boosting NAD+ via supplementation with niacin equivalents has been
proposed as a potential modality capable of promoting healthy aging and negating age-
dependent declines of skeletal muscle mass and function. Objectives We investigated the
efficacy of NAD+-precursor supplementation (tryptophan, nicotinic acid, and nicotinamide)
on skeletal muscle mitochondrial function in physically compromised older adults. Methods
A randomized, double-blind, controlled trial was conducted in 14 (female/male: 4/10) …
proposed as a potential modality capable of promoting healthy aging and negating age-
dependent declines of skeletal muscle mass and function. Objectives We investigated the
efficacy of NAD+-precursor supplementation (tryptophan, nicotinic acid, and nicotinamide)
on skeletal muscle mitochondrial function in physically compromised older adults. Methods
A randomized, double-blind, controlled trial was conducted in 14 (female/male: 4/10) …
